Obesity and related diseases are on the rise worldwide, including type 2 diabetes mellitus, cardiovascular disease and non-alcoholic fatty liver disease. Overweight is also increasingly common among children, indicating that the epidemic will continue to grow [5].

In recent years, many scientific works have appeared indicating the relationship of intestinal microflora with many diseases, in particular, with diabetes mellitus, atherosclerosis, and inflammatory bowel diseases [7, 12]. Human body "collaborates" with the microbiota due to so-called phenomenon of metabolic integration [1]. At the same time, a person receives from microorganisms a number of key metabolites, in particular, short-chain fatty acids (SCFA) [7]. It is known that with the same food intake and exercise regimen, there is a different susceptibility to an increase or decrease in body weight and a possible cause is the different metabolic activity of the human microbiome, including the different composition of the intestinal microflora [2, 5].