Currently, cardiovascular diseases (CVD) remain the main cause of illness and death in the world's population. Studies show that coronary heart disease (CHD) is the main cause of death in the adult population and occupies the main place among the causes of CVD [2]. At the same time, the underlying causes of the pathogenesis of the disease, the causes of atherosclerotic (AS) processes have not yet been fully understood.

Recently, the understanding of the importance of the inflammatory component in the pathogenesis of the development of changes in the vessels in patients with atherosclerosis has noticeably grown. C-reactive protein (CRP), cytokines interleukin-6 (IL-6), tumor necrosis factor-α (TNF – Tumor Necrosis Factor) and its soluble receptors types 1 and 2 (sTNFR1, sTNF-R2) are markers of inflammation [5].