Currently, toxicodermatitis occupies one of the leading places in the general structure of skin diseases, affecting about 6% of the human population [2, 5]. The intestine is a powerful source of endotoxemia and is a determining factor in the development of autosensitization with the subsequent development and progression of toxicodermatitis [3, 4, 6, 7].

One of the most effective methods of detoxification of the body is colon hydrotherapy. This method is widely used in therapy, but there are few data on its use in the treatment of toxicodermatitis.